Bkm120 Clinical Trial

PHASE I - IV CLINICAL TRIALS CURRENTLY ENROLLING
Trial listing current as of February 2015. As a member of US Oncology Research, we are pleased to share this list of Phase 1 - IV clinical trials currently enrolling at Texas Oncology-Fort Worth. of BKM120 with fulvestrant, ... Fetch Here

Bevacizumab - Wikipedia, The Free Encyclopedia
The clinical trial did show that bevacizumab reduced tumor volumes and showed an increase in progression free survival time. It was based on this data that the FDA chose to overrule the recommendation of the panel of advisers. ... Read Article

Colorectal Cancer Clinical Trials Spotlight
Phase I Trial of Irinotecan and BKM120 in Previously Treated Advanced Colorectal Cancer A third trial, scheduled to open soon, is designed to test the new drug Colorectal Cancer Clinical Trials Spotlight Keywords: colorectal cancer clinical trials, colorectal cancer treatment, ... Content Retrieval

PI3K Inhibition Impairs BRCA1/2 Expression And Sensitizes ...
BRCA-Proficient Triple-Negative Breast Cancer to PARP Inhibition PI3K Inhibition Impairs BRCA1/2 Expression and Sensitizes € On the basis of our fi ndings, a clinical trial with BKM120 and olaparib is being initiated in patients with TNBCs. ... View Document

Norwalk Hospital / Whittingham Cancer Center Hematology ...
Norwalk Hospital / Whittingham Cancer Center Hematology & Oncology Clinical 11-23 A Phase III Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor Double Blind Placebo Controlled Study of BKM120 ... Doc Viewer

List Of Actively Accruing Cancer Clinical Trials DST Study ...
CRC.6 A Phase III Trial of 6 Versus 12 Treatments Administered BKM120 as Second-line Therapy in Patients With Advanced Endometrial Carcinoma On hold; Clinical Trials; Open to accrual NCT01423760; List of Actively Accruing Cancer Clinical Trials. ... Document Viewer

Phase Ib Open-label, Multi-center, Dose Escalation And ...
Clinical data presented at ASCO 2012 exploring the BKM120 (PI3K combination in a dose-escalation trial reported clinical activity in a variety of solid tumor types. Cancer Mutation Incidence % BRAF RAS PI3KCA NSCLC 3 30 4 CRC 8 -15 30 -40 32 ... Fetch Content

Targeting Phosphatidylinositide3-Kinase/Akt Pathway By BKM120 ...
Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma Wei-Lin Liu1, being investigated as a single agent in a phase I clinical trial of patients with solid tumors [14]. ... Return Doc

Overlake Stroke Clinical Trial With Dr Chowdhary Q13 02 15 13
Dr. Abhineet Chowdhary with Q13 Fox News today - demonstrating Overlake's newest clinical trial. Penumbra 3D Clinical Trial -- Overlake Medical Center is one ... View Video

Phase I Dose-escalation Study Of Buparlisib (BKM120), An Oral ...
Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, reported in the first-in-man trial in non-Japanese Lollini P et al. Preclinical and preliminary clinical activity of NVP-BKM120, an oral pan-class I PI3K inhibitor, in the brain. Ann Oncol 2012 ... Read Here

TRIALS CLINICAL - University Of Maryland Medical Center
1264GCC Phase III A Phase III Randomized, Double Blind, Placebo Controlled Study of Bkm120 with Fulvestrant, in Postmenopausal Women with Hormone Receptor-Positive HER2-Negative AI Treated, Locally Multiple Site Clinical Trial Evaluating the Safety and Activity of Engineered ... Document Viewer

DST Study Protocol Acronym Project Title Site Status Detail ...
A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients With 1-3 Positive Nodes, BKM120 With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma Open to accrual; NCT01473901 ... Fetch Content

OHC Clinical Trials List 11-14
BKM120!provided! Modular!phase!II Bladder#Clinical#Trials# GUF113:!!GO29293!(Cohort2!CLOSED)! PhaseII! Therapeutic! MPDL3280A!provided! ARandomized,!Multicenter,!OpenFLabel!Trial!ComparingChemotherapy plus!Trastuzumabplus!Pertuzumabversus!Chemotherapy!plus! ... Fetch Content

Issue 02 | Jan 2015
Issue 02 | Jan 2015 SingHealth, which is the inpatient facility for clinical trial related activities. Gefitinib + BKM120 [NCT01570296] Afatinib + IGF-1R [NCT02191891] *Subject to trial inclusion/exclusion criteria ... Read Full Source

Pharmaceuticals Division - Novartis
Including unexpected clinical trial results and additional analysis of existing clinical data; Pharmaceuticals Division: A snapshot of our strategy 3 | Meet Novartis Management | June 17-18, BKM120 BYL719 Longer ... Access Content

LONDON CANCER ALLIANCE - CLINICAL TRIALS
LONDON CANCER ALLIANCE - CLINICAL TRIALS Disease study of BKM120 with fulvestrant, in postmenopausal women with hormone receptor-positive HER2-negative AI treated, locally LCA Clinical Trial Directory - Breast v1.1.xls Author: Chenm ... Get Doc

LONDON CANCER ALLIANCE - CLINICAL TRIALS
LONDON CANCER ALLIANCE - CLINICAL TRIALS of BKM120 plus paclitaxel vs. paclitaxel plus placebo in patients with recurrent or pathway and nivoluMAb clinical Trial Evaluation 141 CHECKMATE 141: An Open Label, Randomized ... Get Document

Buparlisib - Wikipedia, The Free Encyclopedia
It is currently reporting results for the phase 3 BELLE-2 clinical trial for HR+/HER2 advanced endocrine-resistant breast cancer. [1] Encouraging results are reported in some sub-populations - eg. some PI3K mutations. ... Read Article

Clinical Trials - Dana-Farber Cancer Institute
What are clinical trials? studies in which people volunteer to test new treatments. We use clinical trials to learn whether a new treatment works and is safe for people. ... Document Viewer

S/N Tumor Type Title Of Clinical Trial Principal Investigator
S/N Tumor Type Title of Clinical Trial Principal Investigator 1 Breast Phase II Study of Neoadjuvant Docetaxel and Cyclophosphamide in ... Retrieve Full Source

Surgery - AWS
Clinical Trials Reference List Surgery Title Phase Clinicaltrials.gov Identifier Principal Investigator/ a Clinical Trial Rx or Positive Node, Controlled Study of BKM120 With Fulvestrant, in ... Retrieve Doc